Anti-ANG2 Monoclonal Antibody MEDI-3617

Preferred Label : Anti-ANG2 Monoclonal Antibody MEDI-3617;

NCIt synonyms : Anti-ANG2 MoAb MEDI-3617;

NCIt related terms : MEDI-3617;

NCIt definition : A fully human IgG1 monoclonal antibody against angiopoietin 2 (ANG2), with potential antiangiogenic activity. Anti-ANG2 monoclonal antibody MEDI-3617 binds to Ang2 and interferes with the interaction between Ang2 and its receptor TEK tyrosine kinase (Tie2), thereby resulting in the disruption of vascular remodeling. This may inhibit angiogenesis and may eventually lead to an inhibition of tumor cell proliferation.;

UNII : 6RH6DL8R4L;

CAS number : 1415642-51-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1415642-51-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : MEDI-3617;

NCI Metathesaurus CUI : CL428170;

Details

Origin ID

C95704;

UMLS CUI

C3493020;

Currated CISMeF NLP mapping
- MEDI3617 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MEDI3617 [MeSH Supplementary Concept]
- MEDI3617 [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Angiopoietin-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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