paraneoplastic cerebellar degeneration

Preferred Label : paraneoplastic cerebellar degeneration;

MeSH definition : Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686);

MeSH synonym : cerebellar syndromes, paraneoplastic; degeneration, paraneoplastic cerebellar; paraneoplastic cerebellar syndromes; cerebellar syndrome, paraneoplastic; paraneoplastic cerebellar syndrome; cerebellar degeneration, paraneoplastic;

CISMeF acronym : PCD;

MeSH hyponym : paraneoplastic cerebellar degeneration, Anti-Yo-Associated; Paraneoplastic Cerebellar Degeneration, Anti Yo Associated; Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration; Anti Yo Associated Paraneoplastic Cerebellar Degeneration;

MeSH annotation : coord with precoord organ/neopl term histol type;

Details

Origin ID

D020362;

UMLS CUI

C0393534;

Allowable qualifiers
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemically induced [MeSH Qualifier]
- classification [MeSH Qualifier]
- complications [MeSH Qualifier]
- congenital [MeSH Qualifier]
- diagnosis [MeSH Qualifier]
- diagnostic imaging [MeSH Qualifier]
- diet therapy [MeSH Qualifier]
- drug therapy [MeSH Qualifier]
- economics [MeSH Qualifier]
- embryology [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- epidemiology [MeSH Qualifier]
- ethnology [MeSH Qualifier]
- etiology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- mortality [MeSH Qualifier]
- nursing [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiopathology [MeSH Qualifier]
- prevention and control [MeSH Qualifier]
- psychology [MeSH Qualifier]
- radiotherapy [MeSH Qualifier]
- rehabilitation [MeSH Qualifier]
- surgery [MeSH Qualifier]
- therapy [MeSH Qualifier]
- urine [MeSH Qualifier]
- veterinary [MeSH Qualifier]
- virology [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ACE wt Allele [NCIt concept]
- Apoptosis [NCIt concept]
- Des-Gamma Carboxyprothrombin [NCIt concept]
- Dicycloplatin [NCIt concept]
- Division of Cancer Prevention [NCIt concept]
- Programmed cell death [OMIConto structure]
- Protein Induced by Vitamin K Absence-II Measurement [NCIt concept]
- dynein axonemal heavy chain 5 [ORDO Gene]
- dynein axonemal intermediate chain 1 [ORDO Gene]
- osteochondromatosis syndrome [SNOMED Notion]
- paroxysmal pain in patient with cancer pain [Indication]
- programmed cell death [GO term]
- pterin-4 alpha-carbinolamine dehydratase 1 [ORDO Gene]
False automatic mappings
- Ciliary dyskinesia, primary, 1 [OMIM Phenotype]
- PCD Regimen [NCIt concept]
- Premature centromere division [OMIM Phenotype]
- Primary ciliary dyskinesia [ORDO Disease]
- dynein axonemal assembly factor 3 [ORDO Gene]
Indexing information
- Pcd17 protein, mouse [MeSH Supplementary Concept]
- anti-Yo autoantibodies [MeSH Supplementary Concept]
ORDO relation(s)
- Paraneoplastic cerebellar degeneration [ORDO Disease]
Record concept(s)
- paraneoplastic cerebellar degeneration [MeSH concept]
- paraneoplastic cerebellar degeneration, Anti-Yo-Associated [MeSH concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Paraneoplastic Cerebellar Degeneration [NCIt concept]
- Paraneoplastic cerebellar degeneration [MedDRA LLT]
- Paraneoplastic cerebellar degeneration [ICD-11 More detail]
- Paraneoplastic cerebellar degeneration (disorder) [SNOMED CT concept]
- paraneoplastic cerebellar degeneration [Disease (Nov.)]
Validated automatic mappings to BTNT
- anti yo associated paraneoplastic cerebellar degeneration [Disease (Nov.)]

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