NCIt definition : Human MAPK8 wild-type allele is located in the vicinity of 10q11.22 and is approximately
133 kb in length. This allele, which encodes mitogen-activated protein kinase 8 protein,
plays a role in the induction of programmed cell death mediated by both tumor necrosis
factor-alpha and ultraviolet radiation.;
NCIt note : The MAPK8 gene is expressed as four distinct isoforms as a result of alternative splicing.;