" /> Caspase-10 - CISMeF





Preferred Label : Caspase-10;

NCIt synonyms : FAS-Associated Death Domain Protein Interleukin-1B-Converting Enzyme 2; Apoptotic Protease MCH-4; FADD-Like ICE2; FLICE-2; CASP10; MCH4; CASP10 Protein; Interleukin-1B-Converting Enzyme 2; ICE-Like Apoptotic Protease 4; CASP-10; FLICE2; EC 3.4.22.63;

NCIt definition : Caspase-10 (521 aa, 59 kDa) is encoded by the human CASP10 gene. This protein plays a role in proteolysis, apoptosis induction and immunity.;

NCIt note : Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.; Caspase-10 cleaves and activates caspases-3, -4, -6, -7, -8, and -9. (UniProt);

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30/07/2025


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