Fas-Associated death domain proteinMeSH Descriptor
Preferred Label : Fas-Associated death domain protein;
MeSH definition : A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes.
It contains a death effector domain that can interact with death effector domains
found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES
via interaction with this protein plays a role in the signaling cascade that leads
to APOPTOSIS.;
MeSH synonym : fadd, fas-associating protein; fas-associating fadd protein; fas-associating protein with death domain; mort1 protein; fas associating protein with death domain; fadd protein, fas-associating; fadd protein, fas associating; fas-associating protein fadd; fas associating protein fadd; fas associated death domain protein;
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes.
It contains a death effector domain that can interact with death effector domains
found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES
via interaction with this protein plays a role in the signaling cascade that leads
to APOPTOSIS.