Monocyte Differentiation Antigen CD14

Preferred Label : Monocyte Differentiation Antigen CD14;

NCIt synonyms : CD14 Antigen; Lipopolysaccharide Receptor; Myeloid Cell-Specific Leucine-Rich Glycoprotein;

NCIt related terms : CD14;

NCIt definition : Monocyte differentiation antigen CD14 (375 aa, 40 kDa) is encoded by the human CD14 gene. This protein plays a role in the innate immune response to lipopolysaccharide exposure.;

NCI Metathesaurus CUI : CL1375183;

Details

Origin ID

C17488;

UMLS CUI

C5197485;

OMIM relation
- Monocyte differentiation antigen cd14 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- CD14 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Macrophage [NCIt concept]
- Monocyte [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phagocytosis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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