NCIt synonyms : BIMP3; CARMA1; MGC133069; Caspase Recruitment Domain Family, Member 11 Gene; BENTA; Caspase Recruitment Domain Family Member 11 wt Allele; PPBL; IMD11; IMD11A;
NCIt definition : Human CARD11 wild-type allele is located within 7p22 and is 138 kb in length. This
allele, which encodes caspase recruitment domain-containing protein 11, plays a role
in apoptosis regulation and signal transduction. Mutation of the gene is associated
with immunodeficiency types 11A and 11B and with B-cell expansion with NFKB and T-cell
anergy (BENTA).;