E3 Ubiquitin-Protein Ligase SIAH2

Preferred Label : E3 Ubiquitin-Protein Ligase SIAH2;

NCIt synonyms : Siah-2; Seven In Absentia Homolog 2; hSiah2; EC 6.3.2.-, Formerly; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase SIAH2 (324 aa, 35 kDa) is encoded by the human SIAH2 gene. This protein plays a role in the modulation of protein ubiquitin ligation.;

Details

Origin ID

C91765;

UMLS CUI

C1436357;

OMIM relation
- Siah e3 ubiquitin protein ligase family, member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- SIAH2 protein, human [MeSH concept]
- SIAH2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- SIAH2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients