TAF6 wt Allele

Preferred Label : TAF6 wt Allele;

NCIt synonyms : TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa wt Allele; TAFII85; TAFII70; TAF6; TAF2E; TAFII80;

NCIt definition : Human TAF6 wild-type allele is located in the vicinity of 10q24-q25.2 and is approximately 12 kb in length. This allele, which encodes transcription initiation factor TFIID subunit 6 protein, plays a role in the facilitation of transcription.;

NCIt note : Four isoforms have been identified for the TAF6 gene but complete transcripts have been determined for only three isoforms. One isoform has been shown to prevent binding of the TAF9 gene product to the RNA polymerase II transcription factor IID complex; thereby causing both a reduction of the level of cellular transcriptional activity and the initiation of signals that trigger apoptosis. (Entrez Gene);

GenBank Accession Number : NM_005641;

Details

Origin ID

C52608;

UMLS CUI

C1704917;

OMIM relation
- Taf6 rna polymerase II, tata box-binding protein-associated factor, 80-kd [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 7q11.1 [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- DNA Binding [NCIt concept]
- Transcription [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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