NCIt definition : Human SIAH2 wild-type allele is located in the vicinity of 3q25 and is approximately
22 kb in length. This allele, which encodes E3 ubiquitin-protein ligase SIAH2 protein,
is involved in the mediation of ubiquitination. Expression of the gene may play a
role in the development or progression of metastatic prostate neuroendocrine tumor.;