Apoptotic Protease-Activating Factor 1

Preferred Label : Apoptotic Protease-Activating Factor 1;

NCIt synonyms : APAF1; APAF1 Protein; Apoptotic Protease Activating Factor; Apaf-1; Apoptotic Protease Activating Factor 1; Apoptotic Protease Activating Factor-1;

NCIt definition : Apoptotic protease-activating factor 1 (1248 aa, 142 kDa) is encoded by the human APAF1 gene. This protein plays a role in protein-protein interactions, protein modification and apoptosis induction.;

Details

Origin ID

C20930;

UMLS CUI

C1672855;

Currated CISMeF NLP mapping
- apoptotic Protease-Activating factor 1 [MeSH Descriptor]
- apoptotic Protease-Activating factor 1 [MeSH concept]
OMIM relation
- Apoptotic protease activating factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- APAF1 protein, human [MeSH concept]
- APAF1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- APAF1 Gene [NCIt concept]
- Apoptosis Regulation Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Promoter [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Apoptosis DNA Damage Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Caspase Cascade Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- D4-GDI Signaling Pathway [NCIt concept]
- DR3 and DR4/5 Mediated Apoptosis Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
- HIV-1 Nef: Negative Effector Pathway for Fas and TNF-Alpha [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- HSP27 Regulation Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Mitochondria in Apoptotic Signaling Pathway [NCIt concept]
- Mucosal Healing Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Parkinson's Disease Pathway KEGG [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- West Nile Virus Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
- p53 Signaling Pathway BioCarta [NCIt concept]
- p53 Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Caspase Activation [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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