Signal Transducer and Activator of Transcription 5B

Preferred Label : Signal Transducer and Activator of Transcription 5B;

NCIt synonyms : STAT5B; Signal Transducer and Activator of Transcription-5B; Transcription Factor STAT5B;

NCIt definition : Signal transducer and activator of transcription 5B (787 aa, 90 kDa) is encoded by the human STAT5B gene. This protein plays a role in the metabolism of small molecules, transcriptional regulation and signal transduction.;

Details

Origin ID

C28669;

UMLS CUI

C1335959;

OMIM relation
- Signal transducer and activator of transcription 5b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- STAT5B protein, human [MeSH concept]
- STAT5B protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- STAT5B Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- STAT5 Protein Family [NCIt concept]
gene_product_has_gene_product_variant
- STAT5B NP_036580.2:p.N642H [NCIt concept]
- STAT5B NP_036580.2:p.N713_A714insKGKGGG [NCIt concept]
- STAT5B Protein Variant [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- EPO Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB4 Signaling Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Growth Hormone Signaling Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL22 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL3 Signaling Pathway [NCIt concept]
- IL7 Signaling Pathway [NCIt concept]
- Inhibition of Cellular Proliferation by Gleevec Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- DNA Binding [NCIt concept]
- Organogenesis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Receptor Activation [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients