STAT5 Protein Family

Preferred Label : STAT5 Protein Family;

NCIt synonyms : STAT5; Signal Transducer and Activator of Transcription 5; STAT5 Protein; Signal Transducer and Activator of Transcription 5 Protein;

NCIt definition : Two highly conserved members of the signal transducer and activator of transcription (STAT) protein family, STAT5A and STAT5B. Constitutive phosphorylation of STAT5 proteins, which leads to constitutive activation and aberrant expression of STAT5-dependent genes, has been observed in various neoplastic diseases.;

NCI Metathesaurus CUI : CL972099;

Details

Origin ID

C167110;

UMLS CUI

C5235020;

Automatic exact mappings (from CISMeF team)
- Signal transducer and activator of transcription 5a [OMIM gene]
- stat5 transcription factor [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Signal Transducer and Activator of Transcription Family Gene [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
- Transcription Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_chemical_classification_of_gene_product
- Signal Transducer and Activator of Transcription 5A [NCIt concept]
- Signal Transducer and Activator of Transcription 5B [NCIt concept]

Keyword's position in hierarchy(ies) :

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