Transcription Factor

Preferred Label : Transcription Factor;

NCIt definition : Transcription factors are a diverse group of proteins that bind to DNA at specific promoter or enhancer regions. They also bind to DNA-associated proteins to initiate, stimulate, inhibit or terminate transcription. The proteins are often physically associated in a preinitiation complex and contain structural motifs.;

Details

Origin ID

C17207;

UMLS CUI

C0040648;

Automatic exact mappings (from CISMeF team)
- DNA-binding transcription factor activity, RNA polymerase II-specific [GO term]
- Transcription factor name [EDAM data]
- transcription factor hed [MeSH Supplementary Concept]
Biochemical function of gene products
- AP-1 Complex [NCIt concept]
- BHLH Protein [NCIt concept]
- BRAHMA [NCIt concept]
- CCAAT Enhancer Binding Protein [NCIt concept]
- Core-Binding Factor [NCIt concept]
- E1B Protein [NCIt concept]
- E2F Transcription Factor Family [NCIt concept]
- ETS Family Protein [NCIt concept]
- ETV6/RUNX1 Fusion Protein [NCIt concept]
- Early E1A Protein [NCIt concept]
- FOXO Family [NCIt concept]
- GLI Family Protein [NCIt concept]
- Gata-Binding Protein [NCIt concept]
- HIV TAT Protein [NCIt concept]
- Homeobox Family Protein [NCIt concept]
- Hypoxia Inducible Factor Family [NCIt concept]
- Hypoxia-Inducible Factor-1 [NCIt concept]
- MAF Family Protein [NCIt concept]
- MYC Family Protein [NCIt concept]
- Myb Oncogene Protein [NCIt concept]
- NF-AT [NCIt concept]
- NF-kB [NCIt concept]
- Nuclear Factor-I [NCIt concept]
- OSA [NCIt concept]
- Regulatory Factor X Complex [NCIt concept]
- SKI Oncoprotein [NCIt concept]
- STAT5 Protein Family [NCIt concept]
- SWI2/SNF2 [NCIt concept]
- Signal Transducer and Activator of Transcription [NCIt concept]
- Swi3p [NCIt concept]
- TEAD Transcription Factor Family [NCIt concept]
- Trans-Activator Protein BZLF1 [NCIt concept]
- Transcription Initiation Factor IIA [NCIt concept]
- Upstream Stimulatory Factor [NCIt concept]
CISMeF manual mappings
- Transcription factor [OMIConto structure]
Currated CISMeF NLP mapping
- transcription factors [MeSH Descriptor]
- transcription factors [MeSH concept]
See also inter- (CISMeF)
- Transcription factor databases [OMIConto index]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- transcription factor (DOUBLON A VIRER FAIT LE LIEN AVEC BdD) [OMIConto structure]
- transcription factors [MeSH Descriptor]
- transcription factors [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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