ETV6/RUNX1 Fusion Protein

Preferred Label : ETV6/RUNX1 Fusion Protein;

NCIt synonyms : TEL-AML1; TEL/AML1 Fusion Protein; ETV6-RUNX1 Fusion Protein; Transcription Factor ETV6/Runt-Related Transcription Factor 1 Fusion Protein; TEL-AML1 Fusion Protein; ETV6::RUNX1 Fusion Protein;

NCIt definition : A fusion protein encoded by the ETV6/RUNX1 fusion gene. This protein is comprised of the N-terminal DNA binding helix-loop-helix domain of the transcription factor ETV6 protein fused to nearly the entire runt-related transcription factor 1 protein.;

Details

Origin ID

C18040;

UMLS CUI

C0531832;

Currated CISMeF NLP mapping
- TEL-AML1 fusion protein [MeSH concept]
- TEL-AML1 fusion protein [MeSH Supplementary Concept]
OMIM relation
- Ets variant transcription factor 6 [OMIM gene]
- Runt-related transcription factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TEL-AML1 fusion protein [MeSH Supplementary Concept]
- TEL-AML1 fusion protein [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ETV6/RUNX1 Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
- Oncogene [NCIt concept]
gene_product_has_biochemical_function
- Transcription Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Transcriptional Regulation [NCIt concept]
- Tumorigenesis [NCIt concept]
related_to_genetic_biomarker
- ETV6 Gene [NCIt concept]
- RUNX1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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