Oncogene - CISMeF

Preferred Label : Oncogene;

NCIt synonyms : Cancer-Promoting Gene;

NCIt definition : A gene that normally directs cell growth. If mutated or overexpressed in a dominant fashion, it can release the cell from normal restraints on growth. It alone or in concert with other changes, converts the cell into a tumor cell. Alterations can be inherited or caused by an environmental exposure to carcinogens.;

Alternative definition : NCI-GLOSS: A gene that is a mutated (changed) form of a gene involved in normal cell growth. Oncogenes may cause the growth of cancer cells. Mutations in genes that become oncogenes can be inherited or caused by being exposed to substances in the environment that cause cancer.;

Codes from synonyms : CDR0000046259;

Details

Origin ID

C16936;

UMLS CUI

C0029016;

Automatic exact mappings (from CISMeF team)
- carcinogens [MeSH Descriptor]
- genes, sis [MeSH Descriptor]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- BCR/ABL1 Fusion Protein [NCIt concept]
- BCR/ABL1 Fusion Protein p190 [NCIt concept]
- BCR/ABL1 Fusion Protein p210 [NCIt concept]
- BCR/ABL1 Fusion Protein p230 [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.D276G [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.E255K [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.E255V [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.E279K [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.F317L [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.F359V [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.F486S [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.G250E [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.G398R [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.H396P [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.H396R [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.L248V [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.L384M [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.M351T [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.Q252H [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315A [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.V299L [NCIt concept]
- BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.Y253F [NCIt concept]
- CCDC6/RET Fusion Protein [NCIt concept]
- DBL Oncoprotein [NCIt concept]
- ETV6/RUNX1 Fusion Protein [NCIt concept]
- FOS Oncoprotein [NCIt concept]
- FPS-FES Oncoprotein [NCIt concept]
- HPV-11 Protein E6 [NCIt concept]
- HPV-11 Protein E7 [NCIt concept]
- HPV-6 Protein E6 [NCIt concept]
- Myb Oncogene Protein [NCIt concept]
- Oncoprotein [NCIt concept]
- Papillomavirus Protein E2 [NCIt concept]
- Papillomavirus Protein E4 [NCIt concept]
- Papillomavirus Transforming Protein E6 [NCIt concept]
- Papillomavirus Transforming Protein E7 [NCIt concept]
- Probable Protein E4, Human Papillomavirus Type 1 [NCIt concept]
- Probable Protein E4, Human Papillomavirus Type 11 [NCIt concept]
- Probable Protein E4, Human Papillomavirus Type 16 [NCIt concept]
- Probable Protein E4, Human Papillomavirus Type 6 [NCIt concept]
- Probable Protein E5, Human Papillomavirus Type 16 [NCIt concept]
- Protein E6, Human Papillomavirus Type 16 [NCIt concept]
- Protein E6, Human Papillomavirus Type 18 [NCIt concept]
- Protein E7, Human Papillomavirus Type 16 [NCIt concept]
- Protein E7, Human Papillomavirus Type 18 [NCIt concept]
- Protein E7, Human Papillomavirus Type 6 [NCIt concept]
- Protein E7, Human Papillomavirus Type 8 [NCIt concept]
- RET Oncoprotein [NCIt concept]
- Regulatory Protein E2, Human Papillomavirus Type 16 [NCIt concept]
- Regulatory Protein E2, Human Papillomavirus Type 18 [NCIt concept]
- SKI Oncoprotein [NCIt concept]
- SPI1 Oncoprotein [NCIt concept]
- Viral Oncogene Protein [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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