HPV-6 Protein E6

Preferred Label : HPV-6 Protein E6;

NCIt synonyms : HPV 6 E6; Protein E6; Protein E6, Human Papillomavirus Type 6; HPV-6 E6; Human Papillomavirus 6 Protein E6; HPV6 Protein E6; HPV6 E6; HPV 6 Protein E6;

NCIt definition : HPV-6 protein E6 (150 aa, 17 kDa) is encoded by the HPV-6 E6 gene. This protein is involved in viral induction of host cell transformation through the sequestration of cellular tumor antigen p53.;

NCIt note : There are two HPV-6 subtypes (a and b) with highly homologous but not identical protein E6 sequences; these are represented by UniProt Q84291 and P06462, respectively.;

NCI Metathesaurus CUI : CL1664903;

Details

Origin ID

C181986;

UMLS CUI

C0766754;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- E6 protein, human papillomavirus type 6 [MeSH Supplementary Concept]
- E6 protein, human papillomavirus type 6 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Oncogene [NCIt concept]
- Viral Gene [NCIt concept]
gene_product_has_organism_source
- Virus [NCIt concept]
gene_product_plays_role_in_biological_process
- Tumorigenesis [NCIt concept]
is_target
- HPV-6-targeting Immunotherapeutic Vaccine INO-3106 [NCIt concept]
- HPV6/11-targeted DNA Plasmid Vaccine INO-3107 [NCIt concept]

Keyword's position in hierarchy(ies) :

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