HPV6/11-targeted DNA Plasmid Vaccine INO-3107

Preferred Label : HPV6/11-targeted DNA Plasmid Vaccine INO-3107;

NCIt synonyms : HPV-6/11-targeting Immunotherapeutic Vaccine INO-3107; HPV6/11-targeted DNA Plasmid Immunotherapeutic INO-3107;

NCIt definition : A DNA vaccine consisting of plasmids encoding E6 and E7 genes of human papilloma virus subtype 6 (HPV-6) and 11 (HPV-11), with potential immunostimulating and antineoplastic activities. Upon administration via intramuscular electroporation, the HPV-6/11-targeted DNA plasmid vaccine INO-3107 expresses the HPV-6/11 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing HPV6 and/or HPV11 E6 and E7 proteins, resulting in tumor cell lysis. HPV-6/11 infections are associated with aerodigestive malignancies.;

Molecule name : INO-3107; INO 3107;

NCI Metathesaurus CUI : CL1407562;

Details

Origin ID

C173718;

UMLS CUI

C5418022;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- HPV-11 Protein E6 [NCIt concept]
- HPV-11 Protein E7 [NCIt concept]
- HPV-6 Protein E6 [NCIt concept]
- Protein E7, Human Papillomavirus Type 6 [NCIt concept]

Keyword's position in hierarchy(ies) :

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