Protein E7, Human Papillomavirus Type 6

Preferred Label : Protein E7, Human Papillomavirus Type 6;

NCIt synonyms : Oncogene Protein, E7 Human Papillomavirus Type 6; Protein E7; Papillomavirus Type 6 Protein E7; Papillomavirus Type 6 Protein-E7;

NCIt definition : Protein E7 is encoded by the human papillomavirus type 6 E7 gene. This protein is involved in the modulation of the activity of both retinoblastoma protein and histone deacetylases in the infected host cell, which is associated with both viral genome replication and host cell transformation.;

NCIt note : There is no amino acid quantity, molecular weight or SwissProt number associated with this concept because human papillomavirus type 6 has 2 distinct subtypes.;

Details

Origin ID

C17576;

UMLS CUI

C0069527;

Currated CISMeF NLP mapping
- oncogene protein E7, human papillomavirus type 6 [MeSH concept]
- oncogene protein E7, human papillomavirus type 6 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- oncogene protein E7, human papillomavirus type 6 [MeSH concept]
- oncogene protein E7, human papillomavirus type 6 [MeSH Supplementary Concept]
gene_encodes_gene_product
- Oncogene [NCIt concept]
- Viral Gene [NCIt concept]
gene_product_has_organism_source
- Virus [NCIt concept]
gene_product_plays_role_in_biological_process
- Tumorigenesis [NCIt concept]
is_target
- HPV-6-targeting Immunotherapeutic Vaccine INO-3106 [NCIt concept]
- HPV6/11-targeted DNA Plasmid Vaccine INO-3107 [NCIt concept]

Keyword's position in hierarchy(ies) :

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