Preferred Label : HPV-6-targeting Immunotherapeutic Vaccine INO-3106;
NCIt synonyms : HPV-6 E6/E7 DNA Vaccine INO-3106; HPV-6-targeting Immunotherapeutic INO-3106;
NCIt definition : A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma
virus subtype 6 (HPV-6), with potential immunostimulating and antineoplastic activities.
Administered via intramuscular electroporation, HPV-6-targeting immunotherapeutic
vaccine INO-3106 expresses the HPV-6 E6 and E7 proteins, which may elicit a cytotoxic
T-lymphocyte (CTL) response against tumor cells that are expressing those proteins,
resulting in tumor cell lysis. HPV-6 infections are associated with aerodigestive
malignancies.;
Molecule name : INO-3106;
Origin ID : C123378;
UMLS CUI : C4053632;
Semantic type(s)
- concept_is_in_subset
- has_target
