" /> BCR/ABL1 Fusion Protein - CISMeF





Preferred Label : BCR/ABL1 Fusion Protein;

NCIt synonyms : BCR ABL Fusion Protein; BCR-ABL Protein Tyrosine Kinase; BCR/ABL; BCR-ABL1 Fusion Protein; BCR/ABL Chimeric Protein; BCR-ABL Oncoprotein; BCR/ABL Oncoprotein; BCR/ABL Fusion Protein; Breakpoint Cluster Region/Tyrosine-Protein Kinase ABL1 Fusion Protein; BCR::ABL1 Fusion Protein; Breakpoint Cluster Region::Tyrosine-Protein Kinase ABL1 Fusion Protein;

NCIt related terms : BCR-ABL fusion protein;

NCIt definition : A fusion protein encoded by the BCR/ABL1 fusion gene. This protein is comprised of the N-terminus of the breakpoint cluster region protein fused to almost the entire tyrosine-protein kinase ABL1 protein.;

NCIt note : The BCR/ABL1 fusion protein is a constitutively activated tyrosine kinase and has a cytoplasmic localization, in contrast with the mostly nuclear localization of the tyrosine-protein kinase ABL1 protein. (Atlas of Genetics and Cytogenetics in Oncology and Haematology);

Codes from synonyms : CDR0000641107;

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02/05/2024


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