Preferred Label : Bcr-Abl (b3a2)-Derived Peptide Vaccine;
NCIt synonyms : Bcr-Abl b3a2 Derived Peptide Vaccine;
NCIt definition : A peptide vaccine consisting of the bcr-abl b3a2 fusion oncoprotein, frequently expressed
in chronic myelogenous leukemia (CML), with potential antineoplastic activity. Vaccination
with the bcr-abl (b3a2)-derived peptide vaccine may stimulate the host immune system
to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express
the bcr-abl b3a2 fusion protein. Fusion genes in CML typically result from the fusion
of either BCR exon b2 or BCR exon b3 to ABL exon a2, a 'b3a2' or a 'b2a2' fusion.;
Molecule name : CML-VAX B3;
Origin ID : C61310;
UMLS CUI : C1831814;
Semantic type(s)
- concept_is_in_subset
- has_target
