NCIt definition : A fusion protein encoded by the CCDC6/RET fusion gene. This protein is comprised of
the N-terminal leucine zipper of the coiled-coil domain-containing protein 6 fused
to almost the entire C-terminal cytoplasmic domain of the proto-oncogene tyrosine-protein
kinase receptor Ret protein, including the tyrosine kinase domain.;
NCIt note : The CCDC6/RET fusion protein is a constitutively dimerized and activated tyrosine
kinase.;