RUNX1 Gene - CISMeF

Preferred Label : RUNX1 Gene;

NCIt synonyms : Runt-Related Transcription Factor 1 Gene; AML1;

NCIt related terms : RUNX1;

CISMeF acronym : RUNX1;

NCIt definition : This gene plays a role in transcriptional regulation and cytogenetic aberrations are associated with several leukemias.;

Details

Origin ID

C18579;

UMLS CUI

C1335654;

Automatic exact mappings (from CISMeF team)
- RUNX family transcription factor 1 [ORDO Gene]
- Runt-related transcription factor 1 [OMIM gene]
HGNC gene
- RUNX family transcription factor 1 [HGNC gene]
OMIM relation
- Runt-related transcription factor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- RUNX family transcription factor 1 [HGNC gene]
- Runt-related transcription factor 1 [OMIM gene]
concept_is_in_subset
- CCPS Genetics Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Reference Gene Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Childhood Cancer Predisposition Study Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- Runt-Related Transcription Factor 1 [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_abnormality
- RUNX1 Gene Mutation [NCIt concept]
gene_involved_in_molecular_abnormality
- AML1-ETO Fusion Protein Expression [NCIt concept]
- ETV6-RUNX1 Fusion Protein Expression [NCIt concept]
- Germline RUNX1 Gene Mutation [NCIt concept]
- MECOM-RUNX1 Fusion Protein Expression [NCIt concept]
- RUNX1 Gene Mutation [NCIt concept]
- RUNX1 Gene Rearrangement [NCIt concept]
- t(12;21)(p13.2;q22.1) [NCIt concept]
- t(16;21)(q24;q22) [NCIt concept]
- t(3;21)(q26;q22) [NCIt concept]
- t(8;21)(q22;q22) [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- B Acute Lymphoblastic Leukemia with t(12;21)(p13.2;q22.1); ETV6-RUNX1 [NCIt concept]
- B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1 [NCIt concept]
- Hematologic Neoplasm with Germline RUNX1 Mutation [NCIt concept]
- Myelodysplastic Syndrome with Somatic Mutation [NCIt concept]
gene_mapped_to_disease
- Acute Myeloid Leukemia with RUNX1 Mutation [NCIt concept]
- B Acute Lymphoblastic Leukemia with t(12;21)(p13.2;q22.1); ETV6-RUNX1 [NCIt concept]
- B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1 [NCIt concept]
- Familial Platelet Disorder with Associated Myeloid Malignancy [NCIt concept]
- Hematologic Neoplasm with Germline RUNX1 Mutation [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]
genetic_biomarker_related_to
- Core Binding Factor Complex Mutation [NCIt concept]
- Core-Binding Factor [NCIt concept]
- ETV6/RUNX1 Fusion Gene [NCIt concept]
- ETV6/RUNX1 Fusion Protein [NCIt concept]
- Familial Platelet Disorder with Associated Myeloid Malignancy [NCIt concept]
- RUNX1/MECOM Fusion Gene [NCIt concept]
- RUNX1/MECOM Fusion Protein [NCIt concept]
- RUNX1/RUNX1T1 Fusion Gene [NCIt concept]
- RUNX1/RUNX1T1 Fusion Positive [NCIt concept]
- RUNX1/RUNX1T1 Fusion Protein [NCIt concept]
- RUNX1/SH3D19 Fusion Gene [NCIt concept]
- RUNX1/SH3D19 Fusion Protein [NCIt concept]
- RUNX1/YTHDF2 Fusion Gene [NCIt concept]
- RUNX1/ZFPM2 Fusion Gene [NCIt concept]
- RUNX1/ZFPM2 Fusion Protein [NCIt concept]
- RUNX1/ZNF687 Fusion Gene [NCIt concept]
- RUNX1/ZNF687 Fusion Protein [NCIt concept]
- ZFPM2/RUNX1 Fusion Gene [NCIt concept]
- t(12;21)(p13;q22.3)(ETV6/RUNX1) Fusion Transcript in Blood or Tissue by FISH [NCIt concept]
- t(8;21)(q22;q22.3)(RUNX1T1/RUNX1) Fusion Transcript in Blood or Tissue by FISH [NCIt concept]

Keyword's position in hierarchy(ies) :

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