RUNX1/RUNX1T1 Fusion Protein

Preferred Label : RUNX1/RUNX1T1 Fusion Protein;

NCIt synonyms : Acute Myeloid Leukemia-1/Eight-Twenty-One Protein; AML1/MTG8 Fusion Protein; AML1-MTG8 Fusion Protein; Runt-Related Transcription Factor 1/Protein CBFA2T1 Fusion Protein; RUNX1-RUNX1T1 Fusion Protein; AML1-ETO Fusion Protein; AML-1/ETO; AML1-ETO Chimeric Protein; RUNX1::RUNX1T1 Fusion Protein;

NCIt definition : A fusion protein (752 aa, 83 kDa) encoded by the RUNX1/RUNX1T1 fusion gene. This protein is comprised of the N-terminal runt domain of the runt-related transcription factor 1 protein fused to the 577 C-terminal residues of protein CBFA2T1.;

Details

Origin ID

C19892;

UMLS CUI

C1332085;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- RUNX1/RUNX1T1 Fusion Gene [NCIt concept]
gene_product_has_biochemical_function
- Transcription Repressor/Corepressor [NCIt concept]
related_to_genetic_biomarker
- RUNX1 Gene [NCIt concept]
- RUNX1T1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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