RUNX1/YTHDF2 Fusion Gene

Preferred Label : RUNX1/YTHDF2 Fusion Gene;

NCIt synonyms : YTHDF2/RUNX1 Fusion Gene; RUNX1-YTHDF2 Fusion Gene; RUNX1::YTHDF2 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(1;21)(p35-36.1;q22) which fuses exon 5 of the RUNX1 gene to exon 6 of the YTHDF2 gene. This rearrangement is associated with one case of acute myeloid leukemia.;

NCIt note : Translation of the RUNX1/YTHDF2 fusion gene transcript is predicted to produce a truncated form of the runt-related transcription factor 1 protein.;

PubMed : 16858696;

Details

Origin ID

C99300;

UMLS CUI

C1857714;

Automatic exact mappings (from CISMeF team)
- Runt-related transcription factor 1 [OMIM gene]
- Yth n6-methyladenosine rna-binding protein 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
related_to_genetic_biomarker
- RUNX1 Gene [NCIt concept]
- YTHDF2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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