E1B Protein - CISMeF

Preferred Label : E1B Protein;

NCIt synonyms : Adenovirus E1B Protein;

NCIt definition : Human E1B protein (175 aa, 20 kDa) protein is encoded by the human adenovirus 2 (HadV-2) gene. This protein is transcribed by the E1B region of the HadV-2 gene, which is involved in the regulation of E1B protein levels. This protein is an inhibitor of apoptosis induced by TNF or FAS pathways, as well as p53-mediated apoptosis. Without E1B function, virus production is compromised due to the premature death of the host cell.;

Details

Origin ID

C17474;

UMLS CUI

C0101584;

Currated CISMeF NLP mapping
- adenovirus E1B proteins [MeSH concept]
- adenovirus e1b proteins [MeSH Descriptor]
False automatic mappings
- adenovirus E1B protein (368-381) [MeSH concept]
- adenovirus E1B protein (368-381) [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- adenovirus E1B proteins [MeSH concept]
- adenovirus e1b proteins [MeSH Descriptor]
gene_encodes_gene_product
- Oncogene E1B [NCIt concept]
- Viral Gene [NCIt concept]
gene_product_has_biochemical_function
- Transcription Factor [NCIt concept]
gene_product_has_organism_source
- Virus [NCIt concept]
gene_product_plays_role_in_biological_process
- Transcriptional Regulation [NCIt concept]
- mRNA Export [NCIt concept]

Keyword's position in hierarchy(ies) :

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