Signal Transducer and Activator of Transcription - CISMeF
Signal Transducer and Activator of TranscriptionNCIt concept
Preferred Label : Signal Transducer and Activator of Transcription;
NCIt synonyms : STAT Protein; STAT;
NCIt definition : A family of cytoplasmic proteins that are activated by phosphorylation in response
to a large number of cytokines, growth factors, and hormones. They dimerize and translocate
to the nucleus upon activation, where they bind to regulatory cis-elements of specific
target genes.;