Signal Transducer and Activator of Transcription

Preferred Label : Signal Transducer and Activator of Transcription;

NCIt synonyms : STAT Protein; STAT;

NCIt definition : A family of cytoplasmic proteins that are activated by phosphorylation in response to a large number of cytokines, growth factors, and hormones. They dimerize and translocate to the nucleus upon activation, where they bind to regulatory cis-elements of specific target genes.;

Détails

Origin ID

C19618;

UMLS CUI

C1366753;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Signal Transducer and Activator of Transcription Family Gene [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
- Transcription Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_chemical_classification_of_gene_product
- Signal Transducer and Activator of Transcription 1-Alpha/Beta [NCIt concept]
- Signal Transducer and Activator of Transcription 2 [NCIt concept]
- Signal Transducer and Activator of Transcription 3 [NCIt concept]
- Signal Transducer and Activator of Transcription 4 [NCIt concept]
- Signal Transducer and Activator of Transcription 6 [NCIt concept]

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