Signal Transducer and Activator of Transcription 3 - CISMeF
Signal Transducer and Activator of Transcription 3NCIt concept
Preferred Label : Signal Transducer and Activator of Transcription 3;
NCIt synonyms : Acute-Phase Response Factor; STAT3; APRF; Signal Transducer and Activator of Transcription-3;
NCIt definition : Signal transducer and activator of transcription 3 (770 aa, 88 kDa) is encoded by
the human STAT3 gene. This protein plays a role in cytokine signaling and gene expression.;
NCIt note : The small GTPase Rac1 has been shown to bind and regulate the activity of this protein.
PIAS3 protein is a specific inhibitor of this protein.;