E2F Transcription Factor Family

Preferred Label : E2F Transcription Factor Family;

NCIt synonyms : E2F; E2F Transcription Factor; E2F Family;

NCIt definition : A family of transcription factors that bind to the consensus sequence 5'-TTTC[CG]CGC-3' and regulate the transcription of genes involved in cell cycle regulation, DNA repair and DNA replication.;

NCIt note : There are seven human E2F transcription factors.;

Details

Origin ID

C129647;

UMLS CUI

C0146462;

Automatic exact mappings (from CISMeF team)
- E2F transcription factors [MeSH concept]
- E2f transcription factor 1 [OMIM gene]
- e2f transcription factors [MeSH Descriptor]
Biochemical function of gene products
- Transcription Factor E2F1 [NCIt concept]
- Transcription Factor E2F2 [NCIt concept]
- Transcription Factor E2F3 [NCIt concept]
- Transcription Factor E2F4 [NCIt concept]
- Transcription Factor E2F5 [NCIt concept]
- Transcription Factor E2F6 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- E2F transcription factors [MeSH concept]
- e2f transcription factors [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Transcription Factor [NCIt concept]

Keyword's position in hierarchy(ies) :

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