e2f transcription factors

Preferred Label : e2f transcription factors;

MeSH definition : A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.;

MeSH synonym : e2f, transcription factor; transcription factors, e2f; transcription factor e2f; e2f proteins; E2F Transcription Factor; Factor, E2F Transcription; Transcription Factor, E2F;

Is substance : O;

Details

Origin ID

D050684;

UMLS CUI

C0146462;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- E2F Transcription Factor Family [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
- E2f transcription factor 1 [OMIM gene]
Currated CISMeF NLP mapping
- Transcription Factor E2F1 [NCIt concept]
Record concept(s)
- E2F transcription factors [MeSH concept]
Related MeSH Supplementary Concept(s)
- E2FC protein, arabidopsis [MeSH Supplementary Concept]
- E2Fa protein, arabidopsis [MeSH Supplementary Concept]
- E2Fb protein, arabidopsis [MeSH Supplementary Concept]
- E2L2 protein, arabidopsis [MeSH Supplementary Concept]
- efl-1 protein, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- E2F Transcription Factor Family [NCIt concept]

Keyword's position in hierarchy(ies) :

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