" /> SWI2/SNF2 - CISMeF





Preferred Label : SWI2/SNF2;

NCIt synonyms : Snf2p; Transcription Factor TYE3; Regulatory Protein SWI2; SWI/SNF Complex Component SNF2; Swi2p; Regulatory Protein GAM1; Transcription Regulatory Protein SNF2; Mating Type Switch 2/Sucrose Nonfermenting 2; SWI2-SNF2 Protein;

NCIt definition : Nuclear SWI2/SNF2 (SNF2/RAD54 Helicase Family) is a 1703-aa, 194-kD general RNA polymerase II transcription regulator component of the SWI/SNF nucleosome/chromatin remodeling complex involved in global transcriptional activation of induced gene expression and coordinate regulation of phospholipid synthesis. This complex alters chromatin structure to facilitate binding of gene-specific transcription factors. Containing a bromodomain domain and three AT Hook DNA-binding repeats, SWI2/SNF2 exhibits strong similarity to Drosophila brahma. (from Swiss-Prot, and NCI);

NCIt note : SGDID S0005816; Protein_Encoded_by_Gene: SNF2; Protein_Family: SNF2/RAD54 Helicase Family; Protein_Has_Structural_Domain_Or_Motif: Bromodomain Domain, AT Hook DNA-Binding Repeats; Protein_Is_Physical_Part_Of: SWI/SNF;

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15/05/2024


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