Signal Transducer and Activator of Transcription 5A

Preferred Label : Signal Transducer and Activator of Transcription 5A;

NCIt synonyms : STAT5A; STAT5; Signal Transducer and Activator of Transcription-5A; MGF;

NCIt definition : Signal transducer and activator of transcription 5A (794 aa, 91 kDa) is encoded by the human STAT5A gene. This protein is involved in transcriptional regulation, signal transduction and the metabolism of amino acids, carbohydrates and purines.;

Details

Origin ID

C28668;

UMLS CUI

C1366394;

OMIM relation
- Signal transducer and activator of transcription 5a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- STAT5A protein, human [MeSH concept]
- STAT5A protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- STAT5A Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- STAT5 Protein Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CD40/CD40L Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- ERBB4 Signaling Pathway [NCIt concept]
- IL10 Anti-inflammatory Signaling Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL22 Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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