SH2 Domain - CISMeF

Preferred Label : SH2 Domain;

NCIt definition : A region of protein sequence similarity among members of the SRC family of cytoplasmic tyrosine kinases, and other proteins. The SH2 domain usually mediates binding to phosphotyrosine and neighboring residues of target proteins.;

Details

Origin ID

C13339;

UMLS CUI

C0282534;

Automatic exact mappings (from CISMeF team)
- src homology domains [MeSH Descriptor]
Currated CISMeF NLP mapping
- SH2 domain [MeSH concept]
Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
UMLS correspondences (same concept)
- SH2 domain [MeSH concept]
is_structural_domain_or_motif_of_gene_product
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-1 [NCIt concept]
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-2 [NCIt concept]
- Abelson Tyrosine-Protein Kinase 2 [NCIt concept]
- Adapter Molecule crk [NCIt concept]
- B-Cell Linker Protein [NCIt concept]
- Breast Cancer Anti-Estrogen Resistance 3 Protein [NCIt concept]
- Crk-Like Protein [NCIt concept]
- Cytokine-Inducible SH2-Containing Protein [NCIt concept]
- Cytoplasmic Protein NCK2 [NCIt concept]
- Cytoplasmic Tyrosine-Protein Kinase BMX [NCIt concept]
- GRB2-Related Adapter Protein [NCIt concept]
- GRB2-Related Adapter Protein 2 [NCIt concept]
- Growth Factor Receptor-Bound Protein 10 [NCIt concept]
- Growth Factor Receptor-Bound Protein 14 [NCIt concept]
- Growth Factor Receptor-Bound Protein 2 [NCIt concept]
- Growth Factor Receptor-Bound Protein 7 [NCIt concept]
- Guanine Nucleotide Exchange Factor VAV2 [NCIt concept]
- Guanine Nucleotide Exchange Factor VAV3 [NCIt concept]
- Lymphocyte Cytosolic Protein 2 [NCIt concept]
- Megakaryocyte-Associated Tyrosine-Protein Kinase [NCIt concept]
- N-Chimaerin [NCIt concept]
- Non-Receptor Tyrosine-Protein Kinase TYK2 [NCIt concept]
- Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase 1 [NCIt concept]
- Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase 2 [NCIt concept]
- Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha [NCIt concept]
- Phosphatidylinositol 3-Kinase Regulatory Subunit Beta [NCIt concept]
- Phosphatidylinositol 3-Kinase Regulatory Subunit Gamma [NCIt concept]
- Phosphoinositide 3-Kinase Regulatory Subunit 5 [NCIt concept]
- Protein-Tyrosine Kinase 6 [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Src [NCIt concept]
- Proto-Oncogene Vav [NCIt concept]
- Ras GTPase-Activating Protein 1 [NCIt concept]
- Ras and Rab Interactor 1 [NCIt concept]
- SH2 Domain-Containing Protein 1B [NCIt concept]
- SH2 Domain-Containing Protein 3A [NCIt concept]
- SH2 Domain-Containing Protein 3C [NCIt concept]
- SH2B Adapter Protein 1 [NCIt concept]
- SH2B Adapter Protein 2 [NCIt concept]
- SH2B Adapter Protein 3 [NCIt concept]
- SH3 Domain-Binding Protein 2 [NCIt concept]
- SHC-Transforming Protein 1 [NCIt concept]
- SHC-Transforming Protein 2 [NCIt concept]
- SHC-Transforming Protein 3 [NCIt concept]
- SRC Substrate Cortactin [NCIt concept]
- Signal Transducer and Activator of Transcription 1-Alpha/Beta [NCIt concept]
- Signal Transducer and Activator of Transcription 2 [NCIt concept]
- Signal Transducer and Activator of Transcription 3 [NCIt concept]
- Signal Transducer and Activator of Transcription 4 [NCIt concept]
- Signal Transducer and Activator of Transcription 5A [NCIt concept]
- Signal Transducer and Activator of Transcription 5B [NCIt concept]
- Signal Transducer and Activator of Transcription 6 [NCIt concept]
- Signal-Transducing Adaptor Protein 1 [NCIt concept]
- Src-Like-Adapter [NCIt concept]
- Suppressor of Cytokine Signaling 1 [NCIt concept]
- Suppressor of Cytokine Signaling 2 [NCIt concept]
- Suppressor of Cytokine Signaling 3 [NCIt concept]
- Tyrosine-Protein Kinase ABL1 [NCIt concept]
- Tyrosine-Protein Kinase BTK [NCIt concept]
- Tyrosine-Protein Kinase Blk [NCIt concept]
- Tyrosine-Protein Kinase CSK [NCIt concept]
- Tyrosine-Protein Kinase FRK [NCIt concept]
- Tyrosine-Protein Kinase Fer [NCIt concept]
- Tyrosine-Protein Kinase Fes/Fps [NCIt concept]
- Tyrosine-Protein Kinase Fgr [NCIt concept]
- Tyrosine-Protein Kinase Fyn [NCIt concept]
- Tyrosine-Protein Kinase Hck [NCIt concept]
- Tyrosine-Protein Kinase Lck [NCIt concept]
- Tyrosine-Protein Kinase Lyn [NCIt concept]
- Tyrosine-Protein Kinase SYK [NCIt concept]
- Tyrosine-Protein Kinase TEC [NCIt concept]
- Tyrosine-Protein Kinase TXK [NCIt concept]
- Tyrosine-Protein Kinase Yes [NCIt concept]
- Tyrosine-Protein Kinase ZAP-70 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 11 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 22 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 6 [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 7 [NCIt concept]

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