1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-1

Preferred Label : 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-1;

NCIt synonyms : Phosphoinositide Phospholipase C-Gamma-1; Phospholipase C-Gamma-1; PLCG1; Phospholipase C-II; Phosphatidylinositol Phospholipase C; Phospholipase C-148; EC 3.1.4.11; Triphosphoinositide Phosphodiesterase; Phosphoinositide Phospholipase C; PLC-II; Phosphoinositidase C; Inositoltrisphosphohydrolase Monophosphatidylinositol Phosphodiesterase; PLC-148; PLC-Gamma-1;

NCIt definition : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (1290 aa, 149 kDa) is encoded by the human PLCG1 gene. This protein is involved in the intracellular propagation of signals from ligand-dependent receptor-type tyrosine kinases.;

Details

Origin ID

C104824;

UMLS CUI

C1959510;

Automatic exact mappings (from CISMeF team)
- 1-phosphatidylinositol phosphodiesterase (substance) [SNOMED CT concept]
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (substance) [SNOMED CT concept]
- Phospholipase C, gamma-1 [OMIM gene]
- glycerophosphoinositol glycerophosphodiesterase [MeSH Supplementary Concept]
- phosphatidylinositol diacylglycerol-lyase [MeSH Descriptor]
- phosphoinositide phospholipase C [MeSH Descriptor]
- phosphoinositide phospholipase C [MeSH concept]
- phospholipase C beta 1 [ORDO Gene]
- phospholipase C beta 1 [HGNC gene]
- phospholipase C epsilon 1 [ORDO Gene]
- phospholipase C epsilon 1 [HGNC gene]
- phospholipase c gamma [MeSH Descriptor]
OMIM relation
- Phospholipase C, gamma-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PLCG1 protein, human [MeSH Supplementary Concept]
- PLCG1 protein, human [MeSH concept]
- phosphoinositidase C [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLCG1 Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Angiogenesis Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CCR5 Signaling Pathway [NCIt concept]
- Calcineurin Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Cardiac Hypertrophy Pathway [NCIt concept]
- E-Cadherin Signaling Pathway in Keratinocytes [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- EPO Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Ephrin A Forward Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Growth Hormone Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Ion Channel and Phorbal Esters Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- N-Cadherin Signaling Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Nephrin Signaling Pathway in the Kidney Podocyte [NCIt concept]
- Neuronal Survival Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Nitric Oxide Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- PDGFR-alpha Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- Phosphoinositide Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 1 Signaling Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 4 Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Apoptosis Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
- Trka Receptor Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
- VEGFR1 and VEGFR2 Signaling [NCIt concept]
- Vibrio cholerae Infection Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients