SH3 Domain - CISMeF

Preferred Label : SH3 Domain;

NCIt synonyms : SRC Homology Region 3 Domain;

NCIt definition : A region of protein sequence similarity among members of the SRC family of cytoplasmic tyrosine kinases, and other proteins. The SH3 domain is a protein-binding domain that interacts with cytoskeletal proteins.;

Details

Origin ID

C13340;

UMLS CUI

C0282535;

Automatic exact mappings (from CISMeF team)
- src homology domains [MeSH Descriptor]
Currated CISMeF NLP mapping
- SH3 domain [MeSH concept]
Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
UMLS correspondences (same concept)
- SH3 domain [MeSH concept]
is_structural_domain_or_motif_of_gene_product
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-1 [NCIt concept]
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-2 [NCIt concept]
- 55 kDa Erythrocyte Membrane Protein [NCIt concept]
- ABL Interactor 1 [NCIt concept]
- ABL Interactor 2 [NCIt concept]
- Abelson Tyrosine-Protein Kinase 2 [NCIt concept]
- Activated CDC42 Kinase 1 [NCIt concept]
- Adapter Molecule crk [NCIt concept]
- Amphiphysin [NCIt concept]
- Apoptosis-Stimulating of p53 Protein 1 [NCIt concept]
- Apoptosis-Stimulating of p53 Protein 2 [NCIt concept]
- Arf-GAP with SH3 Domain, Ankyrin Repeat and PH Domain-Containing 1 [NCIt concept]
- Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2-Like Protein 1 [NCIt concept]
- Breast Cancer Anti-Estrogen Resistance Protein 1 [NCIt concept]
- CD2-Associated Protein [NCIt concept]
- Cas Scaffolding Protein Family Member 4 [NCIt concept]
- Cdc42-Interacting Protein 4 [NCIt concept]
- Crk-Like Protein [NCIt concept]
- Cytoplasmic Protein NCK2 [NCIt concept]
- Dedicator of Cytokinesis Protein 2 [NCIt concept]
- Disks Large Homolog 1 [NCIt concept]
- Disks Large Homolog 4 [NCIt concept]
- Endophilin-A2 [NCIt concept]
- Epidermal Growth Factor Receptor Kinase Pathway Substrate 8 [NCIt concept]
- Epidermal Growth Factor Receptor Kinase Pathway Substrate 8-Like Protein 1 [NCIt concept]
- Epidermal Growth Factor Receptor Kinase Pathway Substrate 8-Like Protein 2 [NCIt concept]
- Epidermal Growth Factor Receptor Kinase Pathway Substrate 8-Like Protein 3 [NCIt concept]
- F-BAR and Double SH3 Domains Protein 1 [NCIt concept]
- Formin-Binding Protein 1 [NCIt concept]
- GRB2-Related Adapter Protein [NCIt concept]
- GRB2-Related Adapter Protein 2 [NCIt concept]
- Growth Arrest-Specific Protein 7 [NCIt concept]
- Growth Factor Receptor-Bound Protein 2 [NCIt concept]
- Guanine Nucleotide Exchange Factor VAV2 [NCIt concept]
- Guanine Nucleotide Exchange Factor VAV3 [NCIt concept]
- Intersectin-1 [NCIt concept]
- Jouberin [NCIt concept]
- Kalirin [NCIt concept]
- LIM and SH3 Domain Protein 1 [NCIt concept]
- MAGUK p55 Subfamily Member 2 [NCIt concept]
- MAGUK p55 Subfamily Member 3 [NCIt concept]
- MYC Box-Dependent-Interacting Protein 1 [NCIt concept]
- Megakaryocyte-Associated Tyrosine-Protein Kinase [NCIt concept]
- Melanoma Inhibitory Activity Protein 2 [NCIt concept]
- Melanoma-Derived Growth Regulatory Protein [NCIt concept]
- Microtubule-Actin Cross-Linking Factor 1, Isoforms 1/2/3/5 [NCIt concept]
- Myosin-6 [NCIt concept]
- NCK-Interacting Protein with SH3 Domain [NCIt concept]
- Nephrocystin-1 [NCIt concept]
- Neutrophil Cytosol Factor 1 [NCIt concept]
- Neutrophil Cytosol Factor 2 [NCIt concept]
- Neutrophil Cytosol Factor 4 [NCIt concept]
- Non-Receptor Tyrosine-Protein Kinase TNK1 [NCIt concept]
- Obscurin [NCIt concept]
- Oncogene TIM Protein [NCIt concept]
- Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha [NCIt concept]
- Phosphatidylinositol 3-Kinase Regulatory Subunit Beta [NCIt concept]
- Proline-Serine-Threonine Phosphatase-Interacting Protein 1 [NCIt concept]
- Protein PALS1 [NCIt concept]
- Protein-Tyrosine Kinase 6 [NCIt concept]
- Proto-Oncogene Vav [NCIt concept]
- Ras GTPase-Activating Protein 1 [NCIt concept]
- RelA-Associated Inhibitor [NCIt concept]
- Rho GTPase-Activating Protein 26 [NCIt concept]
- Rho Guanine Nucleotide Exchange Factor 5 [NCIt concept]
- Rho Guanine Nucleotide Exchange Factor 7 [NCIt concept]
- SH3 Domain-Containing Kinase-Binding Protein 1 [NCIt concept]
- SH3 Domain-Containing Protein 19 [NCIt concept]
- SH3 and Multiple Ankyrin Repeat Domains Protein 2 [NCIt concept]
- SH3 and Multiple Ankyrin Repeat Domains Protein 3 [NCIt concept]
- SH3 and PX Domain-Containing Protein 2A [NCIt concept]
- SH3 and PX Domain-Containing Protein 2B [NCIt concept]
- SLIT-ROBO Rho GTPase-Activating Protein 2 [NCIt concept]
- SLIT-ROBO Rho GTPase-Activating Protein 3 [NCIt concept]
- SRC Substrate Cortactin [NCIt concept]
- Sorbin and SH3 Domain-Containing Protein 2 [NCIt concept]
- Sorting Nexin-18 [NCIt concept]
- Spectrin Alpha Chain, Erythrocytic 1 [NCIt concept]
- Src Kinase-Associated Phosphoprotein 1 [NCIt concept]
- Src Kinase-Associated Phosphoprotein 2 [NCIt concept]
- Src-Like-Adapter [NCIt concept]
- Tight Junction Protein ZO-1 [NCIt concept]
- Triple Functional Domain Protein [NCIt concept]
- Tyrosine-Protein Kinase ABL1 [NCIt concept]
- Tyrosine-Protein Kinase BTK [NCIt concept]
- Tyrosine-Protein Kinase Blk [NCIt concept]
- Tyrosine-Protein Kinase CSK [NCIt concept]
- Tyrosine-Protein Kinase FRK [NCIt concept]
- Tyrosine-Protein Kinase Fgr [NCIt concept]
- Tyrosine-Protein Kinase Fyn [NCIt concept]
- Tyrosine-Protein Kinase Hck [NCIt concept]
- Tyrosine-Protein Kinase Lck [NCIt concept]
- Tyrosine-Protein Kinase Lyn [NCIt concept]
- Tyrosine-Protein Kinase TEC [NCIt concept]
- Tyrosine-Protein Kinase TXK [NCIt concept]
- Tyrosine-Protein Kinase Yes [NCIt concept]
- Ubiquitin-Associated and SH3 Domain-Containing Protein A [NCIt concept]
- Ubiquitin-Associated and SH3 Domain-Containing Protein B [NCIt concept]
- Unconventional Myosin-Ie [NCIt concept]
- Unconventional Myosin-If [NCIt concept]
- Unconventional Myosin-XV [NCIt concept]

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