phosphoinositide phospholipase C

Preferred Label : phosphoinositide phospholipase C;

MeSH definition : A type C phospholipase with specificity towards PHOSPHATIDYLINOSITOLS that contain INOSITOL 1,4,5-TRISPHOSPHATE. Many of the enzymes listed under this classification are involved in intracellular signaling.;

MeSH synonym : phosphatidylinositide 4,5 bisphosphate phospholipase c; phosphatidylinositide-4,5-bisphosphate phospholipase c; phosphatidylinositol-specific phospholipase c; phosphatidylinositol-4,5-biphosphate-phosphodiesterase; phosphodiesterase, ppi; phosphodiesterase, triphosphoinositide; phosphoinositol specific phospholipase c; phospholipase c, phosphatidylinositol-specific; phospholipase c, polyphosphoinositide; polyphosphoinositide phosphodiesterase; tri-phosphoinositide phosphodiesterase; 1 phosphatidylinositol 4,5 bisphosphate phosphodiesterase; triphosphoinositide phosphodiesterase; 1-Phosphatidyl-D-myo-Inositol-4,5-bisphosphate Inositoltrisphosphohydrolase; 1 phosphatidyl d myo inositol 4,5 bisphosphate inositoltrisphosphohydrolase; inositoltrisphosphohydrolase, 1-phosphatidyl-d-myo-inositol-4,5-bisphosphate; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase; phosphodiesterase, 1-phosphatidylinositol-4,5-bisphosphate; PPI Phosphodiesterase; ptdins(4,5)p2 phosphodiesterase; tri phosphoinositide phosphodiesterase; phospholipase c, phosphatidylinositide-4,5-bisphosphate; phosphatidylinositol 4,5 biphosphate phosphodiesterase; phosphatidylinositol specific phospholipase c; phosphoinositide selective phospholipase c; pip2-phosphoinositidase c; pip2 phosphoinositidase c; PIP2-PLC; phosphodiesterase, polyphosphoinositide; Polyphosphoinositide Phospholipase C;

Registry Number MeSH : EC 3.1.4.11;

Is substance : O;

UNII : EC 3.1.4.11;

Details

Origin ID

D054801;

UMLS CUI

C0089795;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-1 [NCIt concept]
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase [SNOMED Notion]
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (substance) [SNOMED CT concept]
- PDIA3 wt Allele [NCIt concept]
- PLCB4 wt Allele [NCIt concept]
- Phospholipase C, gamma-2 [OMIM gene]
- phospholipase C beta 1 [ORDO Gene]
- phospholipase C beta 1 [HGNC gene]
- phospholipase C epsilon 1 [ORDO Gene]
- phospholipase C epsilon 1 [HGNC gene]
Currated CISMeF NLP mapping
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta-3 [NCIt concept]
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-2 [NCIt concept]
Record concept(s)
- phosphoinositide phospholipase C [MeSH concept]
Related MeSH Supplementary Concept(s)
- PLC3 protein, Arabidopsis [MeSH Supplementary Concept]
- PLC4 protein, Arabidopsis [MeSH Supplementary Concept]
- PLCH1 protein, human [MeSH Supplementary Concept]
- PLCH2 protein, human [MeSH Supplementary Concept]
- PLCZ1 protein, human [MeSH Supplementary Concept]
- Plch1 protein, mouse [MeSH Supplementary Concept]
- Plch2 protein, mouse [MeSH Supplementary Concept]
- Plcz1 protein, mouse [MeSH Supplementary Concept]
- phosphatidylinositol specific phospholipase C, human [MeSH Supplementary Concept]
- phospholipase C epsilon [MeSH Supplementary Concept]
- plc-1 protein, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase [SNOMED Notion]
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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