1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta-3

Preferred Label : 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta-3;

NCIt synonyms : PLC-Beta-3; PLCB3; Phospholipase C Beta 3, Phosphatidylinositol-Specific; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 3; Phosphoinositide Phospholipase C; Phospholipase C Beta 3; Phosphoinositide Phospholipase C-Beta-3; EC 3.1.4.11; Phospholipase C-Beta-3; Phospholipase-C Beta-3; 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta 3;

NCIt definition : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (1234 aa, 139 kDa) is encoded by the human PLCB3 gene. This protein is involved in the biosynthesis of second messengers.;

NCIt note : Protein_Plays_Role_In_Biological_Process: Phospholipid Metabolism;

Details

Origin ID

C34065;

UMLS CUI

C1377871;

Currated CISMeF NLP mapping
- phosphoinositide phospholipase C [MeSH Descriptor]
- phosphoinositide phospholipase C [MeSH concept]
OMIM relation
- Phospholipase C, beta-3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PLCB3 protein, human [MeSH concept]
- PLCB3 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLCB3 Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- EF-Hand Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Gastric Acid Secretion Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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