1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-2

Preferred Label : 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-2;

NCIt synonyms : PLC-IV; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Gamma 2; EC 3.1.4.11; 1-Phosphatidylinositol Phosphodiesterase; Phosphatidylinositol-Specific Phospholipase C-Gamma; Phospholipase-C Gamma-2; Phospholipase C-Gamma-2; PLC-Gamma-2; Phosphoinositide Phospholipase C; PI-Specific PLC Gamma; PLCG2; Phospholipase C Gamma 2; Phosphoinositide Phospholipase C-Gamma-2; Phospholipase C-IV; 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma 2;

NCIt definition : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (1265 aa, 148 kDa) is encoded by the human PLCG2 gene. This protein plays a role in second messenger molecule biosynthesis.;

Details

Origin ID

C18942;

UMLS CUI

C1377870;

Currated CISMeF NLP mapping
- 1-phosphatidylinositol phosphodiesterase [SNOMED Notion]
- phosphatidylinositol Diacylglycerol-Lyase [MeSH concept]
- phosphoinositide phospholipase C [MeSH Descriptor]
- phosphoinositide phospholipase C [MeSH concept]
- phospholipase C gamma 2 [MeSH concept]
False automatic mappings
- 1-phosphatidylinositol phosphodiesterase (substance) [SNOMED CT concept]
OMIM relation
- Phospholipase C, gamma-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PLCG2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLCG2 Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- PH Domain [NCIt concept]
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- Vibrio cholerae Infection Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Fatty Acid Metabolism [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients