Epithelial Cell Signaling Pathway in Helicobacter pylori Infection

Preferred Label : Epithelial Cell Signaling Pathway in Helicobacter pylori Infection;

NCIt synonyms : H. pylori Virulence Factor Pathway;

NCIt related terms : Epithelial cell signaling in Helicobacter pylori infection;

Alternative definition : KEGG: Two major virulence factors of H. pylori are the vacuolating cytotoxin (VacA) and the cag type-IV secretion system (T4SS) and its translocated effector protein, cytotoxin-associated antigen A (CagA).;

KEGG ID : hsa05120;

Details

Origin ID

C91527;

UMLS CUI

C2984332;

Semantic type(s)
- Functional Concept [UMLS semantic type]
has_gene_product_element
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-1 [NCIt concept]
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-2 [NCIt concept]
- ARF GTPase-Activating Protein GIT1 [NCIt concept]
- Activated Caspase-3 [NCIt concept]
- C-C Motif Chemokine 5 [NCIt concept]
- C-X-C Chemokine Receptor Type 1 [NCIt concept]
- C-X-C Chemokine Receptor Type 2 [NCIt concept]
- Caspase-3 [NCIt concept]
- Disintegrin and Metalloproteinase Domain-Containing Protein 10 [NCIt concept]
- Disintegrin and Metalloproteinase Domain-Containing Protein 17 [NCIt concept]
- Dual Specificity Mitogen-Activated Protein Kinase Kinase 4 [NCIt concept]
- Epidermal Growth Factor Receptor [NCIt concept]
- Growth-Regulated Alpha Protein [NCIt concept]
- Heparin-Binding EGF-Like Growth Factor [NCIt concept]
- Hepatocyte Growth Factor Receptor [NCIt concept]
- Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha [NCIt concept]
- Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta [NCIt concept]
- Interleukin-8 [NCIt concept]
- Junctional Adhesion Molecule A [NCIt concept]
- Mitogen-Activated Protein Kinase 10 [NCIt concept]
- Mitogen-Activated Protein Kinase 11 [NCIt concept]
- Mitogen-Activated Protein Kinase 12 [NCIt concept]
- Mitogen-Activated Protein Kinase 13 [NCIt concept]
- Mitogen-Activated Protein Kinase 14 [NCIt concept]
- Mitogen-Activated Protein Kinase 8 [NCIt concept]
- Mitogen-Activated Protein Kinase 9 [NCIt concept]
- Mitogen-Activated Protein Kinase Kinase Kinase 14 [NCIt concept]
- NF-Kappa-B Inhibitor Alpha [NCIt concept]
- Nucleotide-Binding Oligomerization Domain-Containing Protein 1 [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Src [NCIt concept]
- Ras-Related C3 Botulinum Toxin Substrate 1 [NCIt concept]
- Serine/Threonine-Protein Kinase PAK 1 [NCIt concept]
- Tight Junction Protein ZO-1 [NCIt concept]
- Transcription Factor AP-1 [NCIt concept]
- Transcription Factor p65 [NCIt concept]
- Tyrosine-Protein Kinase CSK [NCIt concept]
- Tyrosine-Protein Kinase Lyn [NCIt concept]
- Tyrosine-Protein Phosphatase Non-Receptor Type 11 [NCIt concept]
- V-Type Proton ATPase 116 kDa Subunit A 1 [NCIt concept]
- V-Type Proton ATPase 116 kDa Subunit A 3 [NCIt concept]
- V-Type Proton ATPase Subunit B, Brain Isoform [NCIt concept]
- V-Type Proton ATPase Subunit S1 [NCIt concept]
pathway_has_gene_element
- ADAM10 wt Allele [NCIt concept]
- ADAM17 wt Allele [NCIt concept]
- ATP6AP1 wt Allele [NCIt concept]
- ATP6V0A1 wt Allele [NCIt concept]
- ATP6V1B2 wt Allele [NCIt concept]
- CASP3 wt Allele [NCIt concept]
- CCL5 wt Allele [NCIt concept]
- CHUK wt Allele [NCIt concept]
- CSK wt Allele [NCIt concept]
- CXCL1 wt Allele [NCIt concept]
- CXCL8 wt Allele [NCIt concept]
- CXCR1 wt Allele [NCIt concept]
- CXCR2 wt Allele [NCIt concept]
- EGFR wt Allele [NCIt concept]
- F11R wt Allele [NCIt concept]
- GIT1 wt Allele [NCIt concept]
- HBEGF wt Allele [NCIt concept]
- IKBKB wt Allele [NCIt concept]
- JUN wt Allele [NCIt concept]
- LYN wt Allele [NCIt concept]
- MAP2K4 wt Allele [NCIt concept]
- MAP3K14 wt Allele [NCIt concept]
- MAPK10 wt Allele [NCIt concept]
- MAPK11 wt Allele [NCIt concept]
- MAPK12 wt Allele [NCIt concept]
- MAPK13 wt Allele [NCIt concept]
- MAPK14 wt Allele [NCIt concept]
- MAPK8 wt Allele [NCIt concept]
- MAPK9 wt Allele [NCIt concept]
- MET wt Allele [NCIt concept]
- NFKB1 wt Allele [NCIt concept]
- NFKBIA wt Allele [NCIt concept]
- NOD1 wt Allele [NCIt concept]
- PAK1 wt Allele [NCIt concept]
- PLCG1 wt Allele [NCIt concept]
- PLCG2 wt Allele [NCIt concept]
- PTPN11 wt Allele [NCIt concept]
- RAC1 wt Allele [NCIt concept]
- RELA wt Allele [NCIt concept]
- SRC wt Allele [NCIt concept]
- TCIRG1 wt Allele [NCIt concept]
- TJP1 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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