Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta

Preferred Label : Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta;

NCIt synonyms : Nuclear Factor NF-Kappa-B Inhibitor Kinase Beta; EC 2.7.11.10; IKK2; I-Kappa-B-Kinase Beta; IKK-Beta; I-Kappa-B Kinase 2; IkBKB; IKK-B; NFKBIKB; Serine/Threonine Protein Kinase IKBKB; I-Kappa-B Kinase-Beta;

NCIt definition : Inhibitor of nuclear factor kappa-B kinase subunit beta (756 aa, 87 kDa) is encoded by the human IKBKB gene. This protein is involved in serine phosphorylation, signal transduction and apoptosis inhibition.;

Details

Origin ID

C96385;

UMLS CUI

C1565876;

Automatic exact mappings (from CISMeF team)
- I-kappa B kinase [MeSH Descriptor]
- IkappaB kinase activity [GO term]
- Inhibitor of nuclear factor kappa-b kinase, subunit beta [OMIM gene]
- inhibitor of nuclear factor kappa B kinase subunit beta [ORDO Gene]
OMIM relation
- Inhibitor of nuclear factor kappa-b kinase, subunit beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- IKBKB protein, human [MeSH Supplementary Concept]
- IKBKB protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- IKBKB Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Adipocytokine Signaling Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Atypical NF-kappaB Signaling Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- IL1-Mediated Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- NFKB Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- TRAIL Signaling Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_product_is_physical_part_of
- I-Kappa-B Kinase [NCIt concept]
gene_product_plays_role_in_biological_process
- Negative Regulation of Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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