Transcription Factor AP-1

Preferred Label : Transcription Factor AP-1;

NCIt synonyms : c-JUN Protein; v-jun Avian Sarcoma Virus 17 Oncogene Homolog; JUN; JUN Protein Transcription Factor; Proto-Oncogene c-Jun; JUN Protein; p39; Activator Protein 1; AP1;

NCIt definition : Transcription factor AP-1 (331 aa, 36 kDa) is encoded by the human JUN gene. This protein plays a role in transcriptional activation.;

Details

Origin ID

C17437;

UMLS CUI

C3536909;

Automatic exact mappings (from CISMeF team)
- Cyclin-dependent kinase 5, regulatory subunit 2 [OMIM gene]
- FosB proto-oncogene, AP-1 transcription factor subunit [HGNC gene]
- Jun protooncogene, ap-1 transcription factor subunit [OMIM gene]
- JunD proto-oncogene, AP-1 transcription factor subunit [HGNC gene]
- Proto-Oncogene proteins c-jun [MeSH concept]
- Proto-Oncogene proteins c-jun [MeSH Descriptor]
- c-jun Proto-Oncogenes [MeSH concept]
- genes, jun [MeSH Descriptor]
- genes, jun [MeSH concept]
- obsolete HA1 clathrin adaptor [GO term]
- oncogene protein p65(gag-jun) [MeSH Descriptor]
- replication protein c [MeSH Descriptor]
- transcription factor AP-1 [MeSH concept]
- transcription factor ap-1 [MeSH Descriptor]
OMIM relation
- Jun protooncogene, ap-1 transcription factor subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- JUN Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- bZIP Domain [NCIt concept]
gene_product_is_element_in_pathway
- 4-1BB-Dependent Immune Response Pathway [NCIt concept]
- ATM Signaling Pathway [NCIt concept]
- Agrin Pathway [NCIt concept]
- Androgen Receptor Regulation Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- CCR5 Signaling Pathway [NCIt concept]
- CD40/CD40L Signaling Pathway [NCIt concept]
- Cadmium Induction Pathway [NCIt concept]
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Cardiac Hypertrophy Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- D4-GDI Signaling Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- EPO Signaling Pathway [NCIt concept]
- ERBB2/ERBB3 Signaling Pathway [NCIt concept]
- Endothelin Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
- Fas Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Hypoxia-Inducible Factor Pathway [NCIt concept]
- IFN-Beta Enhancer Pathway [NCIt concept]
- IGF-1 Signaling Pathway [NCIt concept]
- IL1-Mediated Signaling Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2-Mediated Signaling Pathway [NCIt concept]
- IL6 Signaling Pathway [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Inhibition of Cellular Proliferation by Gleevec Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- JNK Signaling in the CD4+ TCR Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Macrophage Differentiation Pathway [NCIt concept]
- Nephrin Signaling Pathway in the Kidney Podocyte [NCIt concept]
- Nerve Growth Factor Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- Oxidative Stress Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- PDGFR-alpha Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Pain Repression Pathway [NCIt concept]
- Presenilin Action in Notch and Wnt Signaling Pathways [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret Signaling Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- Regulation of Retinoblastoma Protein Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 2 Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- TNFR1 Signaling Pathway [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
- TSP-1 Induced Apoptosis Pathway [NCIt concept]
- Telomerase Regulation Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_is_physical_part_of
- AP-1 Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Growth [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- Cantrixil [NCIt concept]

Keyword's position in hierarchy(ies) :

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