Proto-Oncogene proteins c-jun

Preferred Label : Proto-Oncogene proteins c-jun;

MeSH definition : Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.;

MeSH synonym : proto-oncogene products c-jun; p39(c-jun); jun proto-oncogene product p39; jun proto oncogene proteins; jun proto-oncogene proteins; fos associated protein p39; c-jun proteins; c fos associated protein p39; jun proto oncogene product p39; proto oncogene products c jun; c-fos-associated protein p39; proto-oncogene proteins jun; proto oncogene proteins jun; c jun proteins; fos-associated protein p39; p39 c-jun; p39 c jun; proto oncogene proteins c jun;

Related MeSH term : jun D proteins; jun B proteins;

MeSH annotation : /drug eff /ultrastruct permitted; DF: note short X refs;

Is substance : O;

Details

Origin ID

D016755;

UMLS CUI

C0085296;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- AP-1 Complex [NCIt concept]
- JUN Family Protein [NCIt concept]
- Transcription Factor AP-1 [NCIt concept]
Record concept(s)
- Proto-Oncogene proteins c-jun [MeSH concept]
- jun B proteins [MeSH concept]
- jun D proteins [MeSH concept]
Related MeSH Supplementary Concept(s)
- JUN protein, human [MeSH Supplementary Concept]
- Jra protein, Drosophila [MeSH Supplementary Concept]
- JunD protein, human [MeSH Supplementary Concept]
- JunD protein, rat [MeSH Supplementary Concept]
- Oct-1-associated protein 40 [MeSH Supplementary Concept]
- TAM67 peptide [MeSH Supplementary Concept]
- junD protein, mouse [MeSH Supplementary Concept]
- nuclear factor-jun [MeSH Supplementary Concept]
See also
- genes, jun [MeSH Descriptor]
- transcription factor ap-1 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- JUN Family Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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