transcription factor ap-1

Preferred Label : transcription factor ap-1;

MeSH definition : A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.;

MeSH synonym : ap 1 enhancer binding protein; ap-1; ap-1 enhancer-binding protein; enhancer-binding protein, ap-1; activator protein-1; activator protein 1; ap-1 enhancer binding protein; transcription factor AP 1;

MeSH annotation : in genetic transcription; /biosyn /physiol permitted; DF: AP 1;

Wikipedia link : https://en.wikipedia.org/wiki/Transcription factor ap-1;

Is substance : O;

Details

Origin ID

D018808;

UMLS CUI

C0085828;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- DNA-(Apurinic or Apyrimidinic Site) Lyase [NCIt concept]
- FOS wt Allele [NCIt concept]
- Fos proto-oncogene, AP-1 transcription factor subunit [ORDO Gene]
- FosB proto-oncogene, AP-1 transcription factor subunit [HGNC gene]
- Jun protooncogene, ap-1 transcription factor subunit [OMIM gene]
- JunD proto-oncogene, AP-1 transcription factor subunit [HGNC gene]
- Transcription Factor AP-1 [NCIt concept]
- obsolete HA1 clathrin adaptor [GO term]
Currated CISMeF NLP mapping
- AP-1 Complex [NCIt concept]
Indexing information
- 11,10-oxymethylenecyclopent-14-isopropyl-8,11,13-podocarpatriene [MeSH Supplementary Concept]
- 11-hydroxy-14-isopropyl-8,11,13-podocarpatrien-19-al [MeSH Supplementary Concept]
- 11-hydroxy-14-isopropyl-8,11,13-podocarpatrien-19-oic acid [MeSH Supplementary Concept]
- N-(3-(4-benzamido-1H-pyrrolo(3,2-c)pyridin-1-yl)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide [MeSH Supplementary Concept]
Record concept(s)
- transcription factor AP-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- Jra protein, Drosophila [MeSH Supplementary Concept]
- NFAB complex [MeSH Supplementary Concept]
See also
- Proto-Oncogene proteins c-fos [MeSH Descriptor]
- Proto-Oncogene proteins c-jun [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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