JUN Family Protein

Preferred Label : JUN Family Protein;

NCIt synonyms : JUN Proteins;

NCIt definition : Encoded by JUN Family Genes, nuclear leucine zipper JUN Family Proteins (JUN, JUNB, and JUND) can homodimerize, or heterodimerize with nuclear leucine zipper FOS Family Proteins, to form the specific promoter/enhancer DNA-binding AP-1 transcription factor complex that regulates target gene transcription in cell proliferation, differentiation, and transformation. (NCI);

NCI Metathesaurus CUI : CL448418;

Details

Origin ID

C18534;

UMLS CUI

C0085296;

Automatic exact mappings (from CISMeF team)
- Proto-Oncogene proteins c-jun [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Proto-Oncogene proteins c-jun [MeSH Descriptor]
- Proto-Oncogene proteins c-jun [MeSH concept]
gene_encodes_gene_product
- JUN Family Gene [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_physical_part_of
- AP-1 Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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