JUN Family Gene

Preferred Label : JUN Family Gene;

NCIt synonyms : JUN Genes; JUN Proto-oncogene Family;

NCIt definition : JUN Family Genes encode nuclear leucine zipper JUN Family Proteins (JUN, JUNB, and JUND) that can homodimerize, or heterodimerize with nuclear leucine zipper FOS Family Proteins, to form the specific promoter/enhancer DNA binding AP-1 transcription factor complex that regulates target gene transcription in cell proliferation, differentiation, and transformation. (NCI);

NCI Metathesaurus CUI : CL448220;

Details

Origin ID

C17452;

UMLS CUI

C1623430;

Currated CISMeF NLP mapping
- genes, jun [MeSH Descriptor]
- genes, jun [MeSH concept]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- c-jun genes [MeSH concept]
gene_encodes_gene_product
- JUN Family Protein [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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