Mitogen-Activated Protein Kinase 14

Preferred Label : Mitogen-Activated Protein Kinase 14;

NCIt synonyms : MAX-Interacting Protein 2; MAP Kinase Mxi2; MAPK14; p38Alpha EXIP; Stress-Activated Protein Kinase 2A; p38 Mitogen Activated Protein Kinase; MAP-Kinase-14; p38 MAPK; p38 MAP Kinase; Cytokine Suppressive Anti-Inflammatory Drug Binding Protein; CSAIDS Binding Protein; CSBP; SAPK2A; CSAID-Binding Protein; EC 2.7.11.24; MAP Kinase p38 Alpha; Mitogen-Activated Protein Kinase p38 Alpha; MAPK 14; MAP Kinase 14;

NCIt definition : Mitogen-activated protein kinase 14 (360 aa, 42 kDa) is encoded by the human MAPK14 gene. This protein is involved in MAP kinase signaling pathways, serine/threonine phosphorylation and the regulation of gene expression.;

Details

Origin ID

C26369;

UMLS CUI

C1456380;

Currated CISMeF NLP mapping
- Mitogen-Activated protein kinase 14 [MeSH Descriptor]
- Mitogen-Activated protein kinase 14 [MeSH concept]
- p38 Mitogen-Activated protein kinases [MeSH Descriptor]
- p38 Mitogen-Activated protein kinases [MeSH concept]
OMIM relation
- Mitogen-activated protein kinase 14 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MAP Kinase Gene [NCIt concept]
- MAPK14 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Heart [NCIt concept]
- Pancreas [NCIt concept]
- Placenta [NCIt concept]
- Skeletal Muscle Tissue [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- 4-1BB-Dependent Immune Response Pathway [NCIt concept]
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- B-Cell Immune Response Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CCR5 Signaling Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Human Cytomegalovirus Infection Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- MAP Kinase Regulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Map Kinase Inactivation of SMRT Corepressor Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- NFKB Activation Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Oxidative Stress Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- SARS Coronavirus Protease Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Skeletal Myogenesis Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- TSP-1 Induced Apoptosis Pathway [NCIt concept]
- Th2 Cytokine Gene Induction Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- eIF4 Regulation Pathway [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- Ralimetinib Mesylate [NCIt concept]
- p38 MAPK Inhibitor LY3007113 [NCIt concept]

Keyword's position in hierarchy(ies) :

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