p38 Mitogen-Activated protein kinases

Preferred Label : p38 Mitogen-Activated protein kinases;

MeSH definition : A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.;

MeSH synonym : mapk, p38; mitogen-activated protein kinase p38; p38 map kinase; p38 sapk; p38 mapk; p38 protein kinase; protein kinase, p38; mitogen activated protein kinase p38; map kinase, p38; p38 mitogen activated protein kinases; p38 Mitogen-Activated Protein Kinase; p38 Mitogen Activated Protein Kinase;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.24;

Wikipedia link : https://en.wikipedia.org/wiki/P38 mapk;

Is substance : O;

UNII : EC 2.7.11.24;

Details

Origin ID

D048051;

UMLS CUI

C1120843;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Mitogen-Activated Protein Kinase Kinase Kinase 8 [NCIt concept]
- Mitogen-activated protein kinase 14 [OMIM gene]
- Serine/Threonine-Protein Kinase NLK [NCIt concept]
- mitogen-activated protein kinase 14 [HGNC gene]
Currated CISMeF NLP mapping
- Mitogen-Activated Protein Kinase 14 [NCIt concept]
Indexing information
- (1,3-dihydroxyprop-2-yl)-4-(4-fluorophenyl)-5-(2-phenoxypyrimidin-4-yl)imidazole [MeSH Supplementary Concept]
- 1-(4-(3-(4-fluorophenyl)-1H-pyrrolo(3,2-b)pyridin-2-yl)pyridin-2-ylamino)propan-2-ol [MeSH Supplementary Concept]
- 1-(5-(4-chlorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl)-4-methylpiperazine [MeSH Supplementary Concept]
- 3-(3-tert-butyl-6,8-difluoro(1,2,4)triazolo(4,3-a)pyridin-7-yl)-N-cyclopropyl-5-fluoro-4-methylbenzamide [MeSH Supplementary Concept]
- 3-(4-fluorophenyl)-4-pyridin-4-ylquinoline-2(1H)-one [MeSH Supplementary Concept]
- 6-(2-(4-fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo(1,5-a)pyrimidin-3-yl)-2-(2-methylphenyl)pyridazin-3(2H)-one [MeSH Supplementary Concept]
- 6-(5-((cyclopropylamino)carbonyl)-3-fluoro-2-methylphenyl)-N-(2,2-dimethylprpyl)-3-pyridinecarboxamide [MeSH Supplementary Concept]
- 7-amino-5-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)-1,6-naphthyridin-1H-2-one [MeSH Supplementary Concept]
- A 304000 [MeSH Supplementary Concept]
- DP 802 [MeSH Supplementary Concept]
- ITX-5061 [MeSH Supplementary Concept]
- N-(1-(3-chloro-4-hydroxyphenyl)-3-(1,1-dimethylethyl)-1H-pyrazol-5-yl)-N'-((2-((3-(2-((2-hydroxyethyl)thio)phenyl)-1,2,4-triazolo(4,3-a)pyridin-6-yl)thio)phenyl)methyl)-urea [MeSH Supplementary Concept]
- N-(4-(2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide [MeSH Supplementary Concept]
- N-(4-(5-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)acetamide [MeSH Supplementary Concept]
- N-cyano-N'-(2-((8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7-oxo-7,8-dihydropyrido(2,3-d)pyrimidin-2-yl)amino)ethyl)guanidine [MeSH Supplementary Concept]
- N-cyclopropyl-3-(8-(2,4-difluorophenyl)-1-methyl-2-oxo-1,2-dihydropyrido(3,2-d)pyridazin-3-yl)-4-methylbenzamide [MeSH Supplementary Concept]
- N-methoxy-4-methyl-3-(4-(methyl(neopentyl)amino)-6-(4-methyl-1,4-diazepan-1-yl)-1,3,5-triazin-2-ylamino)benzamide [MeSH Supplementary Concept]
- PH 797804 [MeSH Supplementary Concept]
- PHA 666859 [MeSH Supplementary Concept]
- dilmapimod [MeSH Supplementary Concept]
- indole-5-carboxamide [MeSH Supplementary Concept]
- org 48762-0 [MeSH Supplementary Concept]
- pamapimod [MeSH Supplementary Concept]
Record concept(s)
- p38 Mitogen-Activated protein kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- MADD-3 kinase, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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