Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha

Preferred Label : Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha;

NCIt synonyms : IKappaB Kinase; Nuclear Factor NFKappaB Inhibitor Kinase Alpha; IKK-Alpha; I Kappa-B Kinase Alpha; IKBKA; Inhibitor of Nuclear Factor Kappa-B Kinase Alpha Subunit; CHUK; I-Kappa-B Kinase 1; IKKA; IKK1; NFKBIKA; TCF-16; EC 2.7.11.10; Transcription Factor 16; I-Kappa-B Kinase Alpha; IKK-A; I-Kappa-B Kinase-Alpha; Nuclear Factor NF-Kappa-B Inhibitor Kinase Alpha; Conserved Helix-Loop-Helix Ubiquitous Kinase; IkB Kinase Alpha Subunit;

NCIt definition : Inhibitor of nuclear factor kappa-B kinase subunit alpha (745 aa, 85 kDa) is encoded by the human CHUK gene. This protein is involved in the positive regulation of nuclear factor kappa-B signaling.;

Details

Origin ID

C42328;

UMLS CUI

C1565874;

OMIM relation
- Component of nuclear factor kappa-b kinase complex [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CHUK protein, human [MeSH Supplementary Concept]
- CHUK protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CHUK Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- 4-1BB-Dependent Immune Response Pathway [NCIt concept]
- AKT Signaling Pathway [NCIt concept]
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Adipocytokine Signaling Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- B-Cell Immune Response Pathway [NCIt concept]
- CD40L Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- DR3 and DR4/5 Mediated Apoptosis Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- NFKB Activation Pathway [NCIt concept]
- NFKB Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- RELA Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Ras Signaling Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Antiapoptosis Pathway [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- dsRNA Induction Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- I-Kappa-B Kinase [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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