CXCR1 wt Allele

Preferred Label : CXCR1 wt Allele;

NCIt synonyms : IL8RBA; IL8R1; CDw128a; Chemokine, CXC Motif, Receptor 1 Gene; Interleukin 8 Receptor, Type 1 Gene; CMKAR1; C-C-CKR-1; CD181; C-C; CKR-1; CD128; Chemokine (C-X-C Motif) Receptor 1 wt Allele; Interleukin 8 Receptor, Alpha Gene; IL8RA wt Allele; IL8RA;

NCIt definition : Human CXCR1 wild-type allele is located within 2q35 and is approximately 4 kb in length. This allele, which encodes C-X-C chemokine receptor type 1 protein, plays a role in pro-inflammatory cytokine activation, chemoattraction and activation of neutrophils and G-protein activated second messenger signal transduction.;

GenBank Accession Number : NM_000634;

Details

Origin ID

C51371;

UMLS CUI

C1708438;

OMIM relation
- Chemokine, cxc motif, receptor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 2: 218857222-218853076 [NCIt concept]
gene_in_chromosomal_location
- 2q35 [NCIt concept]
gene_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
gene_plays_role_in_process
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Neutrophil Activation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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